Friday’s lone La Liga match features Real Betis (2-0-1) hosting undefeated Real Madrid (3-0-0) at Estadio La Cartuja in Seville, Spain. While Madrid remain prohibitive betting favorites in this one, recent trips to face Real Betis have proved troublesome for Los Blancos, who have dropped points in four straight away meetings – three draws and a defeat – and were held to a 1-1 draw at the Estadio La Cartuja last season.
Real Madrid will look to put its recent struggles in Seville behind it on Friday as it eyes a perfect 4-0 start to the 2026-27 La Liga campaign. Real Madrid is coming off a 4-0 shutout win over Málaga but may need to rotate due to injuries, fitness concerns, and a glamour tie with Inter in the UEFA Champions League league phase on Tuesday. Nonetheless, Real Madrid has been dominant to start the new season, scoring 10 goals while conceding only two. That has helped the club sit atop the standings with nine points and keep pace with rival Barcelona.
Real Betis is also off to a solid start, owning a 2-0-1 record with six points, but is coming off a gut-wrenching 5-2 loss to Levante after opening the season with back-to-back 1-0 wins. As mentioned above, Real Betis has played Real Madrid tough as of late, particularly in Seville, so it will look to keep that trend going on Friday.
Read below for our Real Betis vs. Real Madrid predictions, picks, odds, popular props, and more for Friday’s La Liga matchup.
Real Betis vs. Real Madrid Odds
Even with its recent struggles in Seville, Hard Rock Bet Sportsbook lists Real Madrid as a sizable favorite for Friday’s La Liga match.
- Real Betis: +550
- Real Madrid: -240
- Draw: +400
Real Betis vs. Real Madrid Predictions
There are plenty of ways to get involved in Friday’s Real Betis vs. Real Madrid matchup, so head over to Hard Rock Bet Sportsbook and check out the Stats Hub for soccer betting insights and trends to help you make more informed wagers, like the pick below:
Real Madrid vs. Real Betis Best Bet: Both Teams to Score – Yes (-200)
Both teams have scored at least one goal in each of their first three La Liga matches of the season, while Real Madrid is averaging more than three goals per match on its own. Real Madrid did just shut out Málaga in its last match, but Málaga enters Friday at the bottom of the La Liga standings with just one goal scored through three matches. Real Madrid’s other two opponents, Real Sociedad and Espanyol, both sit below Real Betis in the standings, yet each managed to score against Real Madrid.
The Stats Hub also notes that the Both Teams to Score market has hit in six of Real Betis’ last seven La Liga matches as an underdog, which it is again Friday against Real Madrid.
- Real Madrid vs. Real Betis Game Prop Pick for Sept. 4: Both Teams to Score – Yes (-200)
Popular Props for Real Betis vs. Real Madrid
Kylian Mbappé leads Real Madrid with four goals, 24 shots, and 14 shots on target, making him a popular selection in the prop markets. Mbappé owns four of the top 10 most-bet props among both game and player props heading into Friday’s match:
- Kylian Mbappé – Over 1.5 Shots On Target
- Both Teams To Score – Yes
- Jude Bellingham – To Score or Assist – Yes
Real Betis vs. Real Madrid Match Info
- 📍 Location: Estadio La Cartuja, Sevilla, Spain
- 📅 Date: Friday, Sept. 4
- ⏰ Start Time: 3:00 PM ET
- 📺 Where to Watch: ESPN Deportes, ESPN+
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Referenced odds are subject to change.
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