The Florida State Seminoles (1-1, 0-1 ACC) travel to Tuscaloosa to take on the No. 10 Alabama Crimson Tide (2-0, 1-0 SEC) in a Week 3 college football matchup Saturday at Bryant-Denny Stadium.
Alabama made it to the College Football Playoff quarterfinals last season but fell to eventual champion Indiana in the Rose Bowl, finishing ninth in the AP Poll. The Crimson Tide are off to another good start in 2026 under third-year head coach Kalen DeBoer, starting the season 2-0, including a 45-17 road victory against Kentucky last week.
Alabama’s offense was pretty well-balanced in the win over Kentucky, with quarterback Keelon Russell throwing for 188 yards and a touchdown while the run game totaled 155 yards and three touchdowns. Daniel Hill led the rushing attack with 104 yards and a score.
The Crimson Tide did struggle early in that game, however, with Russell throwing two first-half interceptions and losing a fumble as the Wildcats took a 17-13 lead into the locker room. Alabama’s offense found its rhythm in the second half, while the defense pitched a shutout to complete the comeback win.
Florida State began its season with a 34-17 win over New Mexico State but lost a close 27-24 battle against then-No. 19 SMU last week at home in a game that was delayed for nearly two hours after a power outage at Doak Campbell Stadium. The Seminoles leaned heavily on the run game against SMU, totaling 45 carries for 199 yards and two touchdowns, but couldn’t slow down Kevin Jennings and the Mustangs’ offense despite forcing four turnovers.
Keep reading for Florida State vs. Alabama predictions, picks, and odds ahead of Saturday’s Week 3 matchup in Tuscaloosa.
Florida State vs. Alabama Odds
Hard Rock Bet Sportsbook lists Alabama as a massive home favorite for Saturday’s Week 3 matchup:
Florida State vs. Alabama Predictions
Two historically successful college football programs take the field against one another in an early-season matchup, so make sure to get in on the football betting action at Hard Rock Bet Sportsbook and make wagers on the game like our Florida State vs. Alabama prediction below:
Alabama vs. Florida State Best Bet: Florida State +19.5 (-110)
Alabama’s offense wasn’t necessarily firing on all cylinders despite its convincing Week 2 win and had some early turnovers against Kentucky. Florida State, meanwhile, kept it close against a ranked SMU team in a game that went down to the wire, with the Seminoles forcing four turnovers despite the defense allowing 585 yards of total offense.
Ashton Daniels must put together a better performance at quarterback against a tough Alabama defense for Florida State to have a chance, but Ousmane Kromah and the Seminoles’ run game have been a positive through the first two weeks. If Daniels can step up to the challenge and protect the football, then there’s no reason why Florida State can’t make Saturday’s game closer than the spread suggests.
- Alabama vs. Florida State Spread Pick for Sept. 19: Florida State +19.5 (-110)
Florida State vs. Alabama Betting Splits
Here’s how the action is trending at Hard Rock Bet for Saturday’s matchup:
- Alabama is drawing the majority of moneyline support, with 86.7% of bets and 91.5% of the handle.
- Alabama is also generating more support on the spread, with 80.9% of bets and 87.7% of the handle.
- The Over is attracting most of the action on the total, with 94.4% of bets and 93.4% of the handle.
Florida State vs. Alabama Game Info
- 📍 Where: Bryant-Denny Stadium, Tuscaloosa, AL
- đź“… Date: Saturday, Sept. 19
- ⏰ Kickoff: 3:30 PM ET
- 📺💻 TV/Streaming: ABC
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Referenced odds are subject to change.
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