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New Mexico State visits Sam Houston on Wednesday night for a Conference USA matchup at Elliott T. Bowers Stadium. The Aggies enter at 2-4 overall and 1-1 in conference play, while the Bearkats are 1-5 and 0-2 in CUSA. Kickoff is scheduled for 8 p.m. ET on ESPN2.

New Mexico State returns to action following its bye week, having last played on October 7 in a 22-3 loss at FIU. The Aggies committed three turnovers and managed just one field goal after defeating Western Kentucky 34-13 in their conference opener.

Running back James Jones rushed for 89 yards in the loss to FIU, while linebacker Nick Session recorded a career-high 13 tackles. Gabe Peterson also contributed two sacks and three tackles for loss, but New Mexico State couldn’t overcome its mistakes on offense.

Sam Houston is coming off a 16-3 home loss to Western Kentucky last Wednesday, dropping its third consecutive game and second in conference play. The Bearkats trailed 10-3 at halftime and were held scoreless over the final two quarters.

Quarterback Landyn Locke completed 13 of 30 passes for 112 yards and an interception, while running back MJ Dowdy led the team with 55 rushing yards. The Bearkats finished with just 177 yards of total offense and were penalized nine times for 100 yards.

Wednesday marks the fourth meeting between these programs, with New Mexico State holding a 2-1 advantage in the all-time series. Sam Houston won the last matchup in Huntsville, defeating the Aggies 31-11 in 2024.

NMSU vs. Sam Houston Odds Today

New Mexico State enters Wednesday night’s matchup as a 2.5-point road favorite at Hard Rock Bet Sportsbook:

  • Point Spread: New Mexico State -2.5 (-120) | Sam Houston +2.5 (+100)
  • Moneyline: New Mexico State -150 | Sam Houston +125
  • Total: Over 44.5 (-110) | Under 44.5 (-110)

Referenced odds subject to change.

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New Mexico State vs. Sam Houston Prediction

Sam Houston +2.5 (+100): New Mexico State has yet to win away from home this season, dropping all three of its road games. The Aggies have struggled to produce consistent offense outside Las Cruces, scoring just 39 combined points across those three contests.

Sam Houston was in a similar spot last Wednesday, hosting Western Kentucky as a slight home underdog but failing to take advantage. The Bearkats now get another opportunity at home against a New Mexico State team that hasn’t won on the road.

While Sam Houston’s offense remains a concern, its defense has been competitive. The Bearkats are allowing approximately 338 yards per game, including fewer than 140 passing yards per contest. They’ve also held five of their six opponents below 200 passing yards.

They now have an encouraging matchup against a New Mexico State passing attack that has struggled with limiting turnovers. The Aggies have thrown seven interceptions this season, including two against FIU, and could have trouble moving the ball consistently against Sam Houston’s secondary.

The Bearkats have also been competitive in their previous meetings with New Mexico State at home, winning 31-11 in 2024.

With New Mexico State still searching for its first road victory and Sam Houston getting another chance here as a home underdog, I’ll take the Bearkats and the points.

  • Best Bet: Sam Houston +2.5 (+100)

Betting Splits at Hard Rock Bet

  • Moneyline: Sam Houston has received 66% of all ML tickets and 54% of the handle.
  • Spread: New Mexico State -2.5 has pulled in 61% of spread bets and 64% of the money at Hard Rock Bet.
  • Total: Over 44.5 accounts for 51% of tickets, while Under 44.5 has drawn 56% of the handle.

NMSU vs. Sam Houston Game Info

  • šŸŸļø Location: Elliott T. Bowers Stadium – Huntsville, Texas
  • šŸ“… Date: Wednesday, October 21
  • ā° Start Time: 8 p.m. ET
  • šŸ“ŗ Where to Watch: ESPN2

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Michael Sciangula

Michael Sciangula is a New Jersey-based sports betting and online casino writer. He has contributed iGaming content to several publications over the last half decade including the Action Network, New York Post and Philadelphia Inquirer. Contact Michael at michael.sciangula at hardrockdigital.com.