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Italy vs. Belgium UEFA Nations League Sept. 25

Italy and Belgium are in action Friday for a UEFA Nations League match at Stadio Olimpico in Rome, Italy. Both nations are in League A, Group 1 alongside France and Türkiye as they begin their 2026-27 UEFA Nations League campaigns.

Italy won back-to-back international friendlies in June but is looking to move past its heartbreaking loss to Bosnia and Herzegovina in UEFA World Cup qualifying. Italy played Bosnia and Herzegovina to a 1-1 draw before losing 4-1 on penalties, which kept the Azzurri out of the 2026 World Cup. Italy now begins a new chapter with Roberto Mancini back as manager for his second stint with the national team.

Belgium, on the other hand, qualified for the World Cup and made a deep run to the quarterfinals, which included a Round of 16 win over the United States. However, Belgium ran into eventual champion Spain and suffered a 2-1 loss in the quarterfinals. The Belgium men’s national team hasn’t played since that defeat.

Read below for our Italy vs. Belgium predictions, picks, odds, and more for Friday’s UEFA Nations League matchup.

Italy vs. Belgium Odds

Italy, Belgium, and the draw all have plus-money odds at Hard Rock Bet Sportsbook, but Italy is listed as the home favorite.

Three-Way Moneyline:

  • 🇮🇹 Italy: +110
  • 🇧🇪 Belgium: +220
  • Draw: +250
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Italy vs. Belgium Predictions

It’s the early stages of the UEFA Nations League, but that doesn’t mean there aren’t intriguing storylines to follow as these teams begin their pursuit of the title. Don’t miss your chance to get in on the soccer betting action at Hard Rock Bet Sportsbook, where you can make wagers like our Italy vs. Belgium prediction below:

Belgium vs. Italy Best Bet: Both Teams to Score – Yes (-190)

Neither team has played together in quite some time, particularly Italy, whose men’s national team last took the field on June 7. However, there are still plenty of extremely talented players set to take the pitch on both sides. Just because these players haven’t been playing alongside one another regularly doesn’t necessarily mean this will be a sloppy match that ends in a scoreless draw.

Italy has scored at least one goal in each of its last 11 matches dating back to June 2025. While Belgium played Iran to a 0-0 draw during the group stage of the 2026 World Cup, it has since scored at least once in each of its last four matches, averaging 3.25 goals per match during that span.

  • Belgium vs. Italy Game Prop Pick for Sept. 25: Both Teams to Score – Yes (-190)

Popular Props for Italy vs. Belgium

The game prop and player prop markets are heating up as kickoff approaches, with Both Teams to Score among the most popular selections for Italy vs. Belgium:

  • Both Teams To Score – Yes
  • Belgium Total Goals – Over 0.5
  • Romelu Lukaku – Anytime Goalscorer

Italy vs. Belgium Match Info

  • 📍 Location: Stadio Olimpico, Rome, Italy
  • 📅 Date: Friday, Sept. 25
  • ⏰ Start Time: 2:45 PM ET
  • 📺 Where to Watch: FS2
  • 🏆 Stage: UEFA Nations League – League A, Group 1

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Referenced odds are subject to change.

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Michael Hennelly

Michael has been an active sports contributor for multiple publications since graduating from Penn State in 2024. While sports play a major role in his life (in the best way), he also enjoys spending time with family and friends. Contact Michael at michael.hennelly at hardrockdigital.com.