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The Memphis Tigers (7-2, 4-1 American) travel to Tampa, Florida, Thursday night to take on the South Florida Bulls (6-3, 2-3 American) for a Week 11 college football matchup at Raymond James Stadium.

Find our Memphis vs. USF predictions, picks, and odds below as the Tigers look to stay in the American Conference championship race.

Memphis vs. USF Odds

Memphis needs to keep stacking wins to finish the season, and Hard Rock Bet Sportsbook lists the Tigers as road favorites to do just that Thursday night:

  • Moneyline: Memphis -180, South Florida +145
  • Spread: Memphis -3.5 (-110), South Florida +3.5 (-110)
  • Total: Over 50.5 Points (-110), Under 50.5 Points (-110)
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Memphis vs. USF Predictions

It’s only a two-game college football slate Thursday, but that doesn’t mean there aren’t still plenty of ways to get involved. Head over to Hard Rock Bet Sportsbook to explore the available football betting markets and make wagers on the game, like our Memphis vs. USF prediction below:

USF vs. Memphis Best Bet: Over 50.5 Points (-110)

Memphis features one of the top-ranked offenses in the country, averaging 37.6 points and 513.3 total yards per game while excelling in both the passing attack and the run game. The Tigers are averaging 45 points per game over their last two contests and, on the flip side, are allowing 23.6 points per game to opponents this season.

Tigers quarterback Marcus Stokes has been incredible this year, ranking third in passing yards and second in passing touchdowns in the conference while also rushing for 261 yards and three touchdowns. Running back Jaylin Carter ranks third in rushing yards and has 11 total touchdowns, while four pass catchers have 400 or more receiving yards this season, with tight end Hunter Tipton leading the team with 495 yards.

Memphis also has the benefit of playing fresh off a bye week, which could result in more explosive plays with the players having had a chance to rest and prepare for the final push of the season.

South Florida’s offense is also solid, though not as dangerous as Memphis’. The Bulls are averaging 25.9 points per game, relying heavily on running back D.J. Crowther, who has 689 rushing yards and seven rushing touchdowns this year.

Crowther did get banged up in last week’s game against East Carolina, so his status is worth monitoring closer to kickoff. Even if he’s able to play, Crowther could see limited action throughout the game, meaning others in the Bulls’ offense will have to step up to keep pace with the Tigers.

  • South Florida vs. Memphis Total Pick for Nov. 12: Over 50.5 Points (-110)

Memphis vs. South Florida Betting Splits

Here’s how the action is trending at Hard Rock Bet for Thursday night’s American Conference showdown in Tampa:

  • USF is the underdog but is generating more moneyline support, with 74% of wagers and 94% of the money.
  • The Bulls are also seeing more support on the spread, with 69% of wagers and 84% of the money.
  • The majority of action on the total is going to the Over, with 85% of wagers and 95% of the money.

Memphis vs. South Florida Preview for Thursday Night

The top of the American Conference standings is crowded heading into the final weeks of the 2026 season, and Memphis is right there. North Texas leads the conference with an undefeated 5-0 American record, but Memphis, along with UTSA and Army, is right in the championship game conversation with four conference wins apiece.

Memphis won two games in a row to start the year, lost to Boise State, went on a three-game winning streak, lost to Tulane, and has now won back-to-back games entering Week 11. The first of those two wins was a 41-34 overtime victory against East Carolina, followed by a 49-22 win over Army on Oct. 31 before its bye week.

Tigers quarterback Marcus Stokes put together yet another sensational performance in the win over Army, completing 29 of 35 passes for 371 yards and four touchdowns. He also averaged 4.3 yards per carry and rushed for a touchdown in the win.

Three Memphis players scored two touchdowns each in that win over Army. Running back Jaylin Carter rushed for two scores, while wide receivers Jermane Hayes and Jemyri Davis each hauled in two touchdown catches, showcasing just how dangerous this top-ranked Tigers offense is in all facets.

South Florida began the year 4-0 but has since lost three of its last five games, including a 20-17 loss to East Carolina last week. Bulls starting quarterback Michael Van Buren Jr. missed last week’s game due to injury after exiting the previous contest, a 30-10 win over UAB.

Backup quarterback Luke Kromenhoek wasn’t much of a factor through the air when he replaced Van Buren, passing for just 39 yards in the win over UAB, but he did rush for 92 yards. He was much more effective in the passing game as USF’s starting quarterback last week, completing 17 of 21 passes for 179 yards and a touchdown. However, outside of running back D.J. Crowther totaling 153 yards, the Bulls’ offense couldn’t get much going in the three-point loss.

Again, Crowther got banged up in last week’s loss, and his status is uncertain for Thursday night. Also keep an eye on Van Buren’s status, as he could potentially make his return from injury at quarterback for USF. If not, Kromenhoek will be in line for his second consecutive start.

Memphis vs. USF Game Info

  • šŸ“ Where: Raymond James Stadium, Tampa, FL
  • šŸ“… Date: Thursday, Nov. 12
  • ā° Kickoff: 8:00 PM ET
  • šŸ“ŗšŸ’» TV/Streaming: ESPN

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Referenced odds are subject to change.

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Michael Hennelly

Michael has been an active sports contributor for multiple publications since graduating from Penn State in 2024. While sports play a major role in his life (in the best way), he also enjoys spending time with family and friends. Contact Michael at michael.hennelly at hardrockdigital.com.