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The San Diego Padres bring MLB’s longest active winning streak into Chavez Ravine on Tuesday night as they open a three-game series against the Los Angeles Dodgers. First pitch is scheduled for 10:10 p.m. ET on TBS.

San Diego has won five consecutive games and 13 of its last 14, climbing to 87-69 with six games remaining in the regular season. The Padres are currently tied with Chicago for the top National League Wild Card spot, one game ahead of Philadelphia and five games clear of Arizona. A win Tuesday combined with an Arizona loss would officially send San Diego to the postseason.

Los Angeles is rolling into the series as well. The Dodgers swept San Francisco over the weekend to extend their winning streak to four games and improve to 96-60. They have already secured their fifth straight NL West title, but still have something to play for, sitting two games behind the Milwaukee Brewers for the National League’s No. 1 seed.

The Dodgers will also be without Shohei Ohtani for the series opener. Ohtani remains on the injured list while dealing with left knee and right biceps issues, but he is expected to be activated when eligible on Wednesday.

Michael King gets the ball for San Diego with a 12-9 record, 3.03 ERA and 154 strikeouts on the season. The right-hander is 4-0 with a 1.41 ERA across his last five starts and has already made three starts against the Dodgers this season. His best came May 18, when King struck out nine across seven scoreless innings in a 1-0 Padres victory at home.

Padres vs. Dodgers Odds Today

The Dodgers jump out as slight home favorites at Hard Rock Bet Sportsbook:

  • Moneyline: Padres (+105), Dodgers (-125)
  • Run Line: Padres +1.5 (-195), Dodgers -1.5 (+160)
  • Total: Over 8.5 (-105), Under 8.5 (-115)
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Best Bet for Padres vs. Dodgers

Padres Moneyline (+105): The Padres have put themselves in position to secure a third consecutive postseason appearance by winning 13 of their last 14 games, including five straight entering this series. They’re now tied with the Cubs for the top Wild Card spot and have an opportunity to clinch a playoff berth before closing the regular season with three games against Arizona.

King has consistently pitched well against Los Angeles throughout his career. Across eight appearances against the Dodgers, King is 3-1 with a 2.95 ERA, 1.08 WHIP and 45 strikeouts across 42.2 innings, including two particularly strong starts this season.

He tossed seven scoreless innings with nine strikeouts in a 1-0 win over Los Angeles on May 18. He was sharp again at Dodger Stadium in July, carrying a 3-0 lead into the seventh inning before the Dodgers went on to rally for a 4-3 victory against San Diego’s bullpen.

King now returns to Chavez Ravine with a 4-0 record and 1.41 ERA over his last five starts, while San Diego has climbed into a tie for the top Wild Card position during its late-season surge.

Los Angeles has won four straight as well, but its lineup remains without Shohei Ohtani, who is on the injured list and expected to return on Wednesday.

With King’s track record against this lineup and the Padres entering Los Angeles on fire with playoff positioning up for grabs, take San Diego at plus money to make it six straight.

  • Best Bet: Padres Moneyline (+105)

Padres vs. Dodgers Betting Splits

Hard Rock Bet players have leaned toward Los Angeles, particularly on the run line:

  • The Dodgers have received 79.4% of moneyline tickets and 75.7% of the money wagered.
  • Dodgers -1.5 accounts for 52.3% of run line tickets but a much larger 81.5% share of the handle.
  • Over 8.5 holds a narrow advantage with 50.5% of tickets, while Under 8.5 has attracted 60% of the total handle.

Top 5 Most-Bet Player Props

Fernando Tatis Jr. occupies the first two spots for Tuesday’s most-bet player props:

  1. Fernando Tatis Jr. – Over 0.5 Home Runs
  2. Fernando Tatis Jr. – Over 0.5 Hits
  3. Mookie Betts – Over 0.5 Hits
  4. Jackson Merrill – Over 0.5 Hits
  5. Freddie Freeman – Over 0.5 Hits

Padres vs. Dodgers Game Info

  • 📍 Where: UNIQLO Field at Dodger Stadium, Los Angeles, California
  • 📅 Date: Tuesday, September 22
  • First Pitch: 10:10 PM ET
  • 📺 TV: TBS

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Michael Sciangula

Michael Sciangula is a New Jersey-based sports betting and online casino writer. He has contributed iGaming content to several publications over the last half decade including the Action Network, New York Post and Philadelphia Inquirer. Contact Michael at michael.sciangula at hardrockdigital.com.