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Thursday’s MLB slate concludes with the San Diego Padres (12-6) going for a three-game sweep of the Seattle Mariners (8-11) at Petco Park. The Mariners haven’t been able to figure out the Padres, even after entering the series hot following a four-game sweep of the Houston Astros.

The Padres got off to a slow start to the 2026 season but enter Thursday night’s series finale on a seven-game winning streak. San Diego understands the importance of stacking wins while competing in a division alongside the defending back-to-back World Series champion Los Angeles Dodgers.

Mariners vs. Padres Game Info

  • 📍 Where: Petco Park, San Diego, CA
  • 📅 Date: Thursday, April 16
  • First Pitch: 8:40 PM ET
  • 📺💻 TV/Streaming: MLB.TV, MLB Network
  • Probable Pitchers:
    • Mariners: Luis Castillo
    • Padres: Walker Buehler

Mariners vs. Padres Current Odds

The Mariners enter as road favorites at Hard Rock Bet Sportsbook with the starting pitching advantage behind Luis Castillo, despite dropping the first two games of this three-game series:

  • Moneyline: Mariners -120, Padres +100
  • Run Line: Mariners -1.5 (+140), Padres +1.5 (-170)
  • Total (Runs): Over 8.5 (-110), Under 8.5 (-110)

Gone Slumping: Mariners & Padres Stars’ Quiet Start

The Mariners had high expectations heading into the 2026 season but enter Thursday night’s matchup three games below .500. Despite the slow start, Hard Rock Bet Sportsbook still lists Seattle with the third-best odds to win the 2026 World Series at +1400 and the second-best odds to win the AL pennant at +500.

A large reason for Seattle’s struggles has been the lack of production from Julio Rodríguez, Cal Raleigh, and Josh Naylor, who are all batting below .200 with just 10 extra-base hits combined. Thursday night would be an ideal time for them to get going to avoid a sweep before a three-game series against AL West rival Texas Rangers begins Friday night.

The Padres, meanwhile, sit in second place in the NL West with one of the best records in Major League Baseball. While San Diego is hot as a team, a few of its star players are still trying to find their groove. Fernando Tatís Jr. is still searching for his first home run of the season, and Manny Machado is hitting just .185 through 54 at-bats.

Top 5 Most-Bet Player Props for SEA-SD

The baseball betting markets are heating up for this game, including these five most-bet player props heading into first pitch:

  1. Cal Raleigh – Home Runs Over 0.5
  2. Jackson Merrill – Home Runs Over 0.5
  3. Jackson Merrill – Hits Over 0.5
  4. Cal Raleigh – Hits Over 0.5
  5. Fernando Tatís Jr. – Hits Over 0.5

Referenced odds are subject to change.

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Michael Hennelly

Michael has been an active sports contributor for multiple publications since graduating from Penn State in 2024. While sports play a major in his life (in the best way), he also enjoys spending time with family and friends. Contact Michael at [email protected].