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The NFL is back across the pond for the second straight week after the Indianapolis Colts beat the Washington Commanders in London in Week 4. This time, London’s de facto home team, the Jacksonville Jaguars (3-1), is set to take on the Philadelphia Eagles (2-2) at Tottenham Hotspur Stadium to kick off Sunday’s Week 5 slate.

Sunday’s game will mark the Jaguars’ 15th appearance in London since 2013, the most by any team in the NFL. It will also be the first of two consecutive games Jacksonville will play there, as the Jaguars will take on AFC South rival Houston in Week 6 at Wembley Stadium.

Jacksonville will look to keep its momentum going against Philadelphia, entering the matchup on a two-game winning streak after beating New England 35-6 two weeks ago and then earning a 22-17 road win over Cincinnati last week. Jaguars quarterback Trevor Lawrence played a stellar game against Cincinnati, while the defense intercepted Bengals quarterback Joe Burrow twice in the win.

After a frustrating 2025 season, the Eagles are enduring many of the same struggles they faced last year through the first four weeks of 2026. The offense has been underwhelming and inconsistent, forcing what’s still a very talented defense to spend far more time on the field than it should, ultimately leading to some breakdowns throughout the course of games.

Philadelphia could easily be 0-4 right now if a few things here and there hadn’t gone its way. However, the Eagles could just as easily be 3-1. They managed to squeak past Washington and Tennessee in tightly contested games to start the season 2-0 but have since suffered an ugly loss to Case Keenum and Chicago in Week 3 before collapsing against the Los Angeles Rams last week. Philadelphia allowed L.A. to score 14 unanswered fourth-quarter points, blowing its lead in a 24-20 loss to drop its second consecutive game.

As if things couldn’t get any worse for the Eagles, they will now be without multiple starting offensive linemen after 14-year veteran Lane Johnson announced his abrupt retirement following Week 4, Pro Bowl center Cam Jurgens was traded to Baltimore ahead of Week 5, and Landon Dickerson remains out with a knee injury. Second-year lineman Drew Kendall, who has started at center for the last three weeks, is also out Sunday with a knee injury.

Philadelphia is also dealing with injuries to several other key players, including running back Saquon Barkley and wide receiver DeVonta Smith, both of whom have been ruled out for Week 5. However, the Eagles will get a much-needed boost with tight end Dallas Goedert returning from a two-game absence and Pro Bowl linebacker Zack Baun also getting back on the field after missing Week 4 due to a concussion.

Check out our Eagles vs. Jaguars best player props, touchdown bets, predictions, and odds below for Sunday’s Week 5 London matchup.

Eagles vs. Jaguars Odds

The Jaguars are listed as sizable favorites at Hard Rock Bet Sportsbook for this Week 5 London matchup, while the Eagles are looking to overcome the numerous injuries they’re dealing with:

  • Moneyline: Jaguars -400, Eagles +300
  • Spread: Jaguars -7.5 (-115), Eagles +7.5 (-105)
  • Total: Over 41.5 Points (-110), Under 41.5 Points (-110)
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Best Player Prop and Touchdown Bets for Eagles vs. Jaguars

Hard Rock Bet Sportsbook offers plenty of ways to get involved in NFL games with a wide variety of football betting markets, along with its Stats Hub, which provides insights and trends for every matchup. We used the Stats Hub to help pick out two of the best player prop bets for Eagles vs. Jaguars, including an anytime touchdown wager:

Trevor Lawrence Anytime Touchdown (+300)

This anytime touchdown prediction doesn’t have any specific insights or trends from the Stats Hub directly supporting it, but we still used a few other trends to help inform the pick, along with several matchup factors that make it a realistic possibility.

Trevor Lawrence isn’t Lamar Jackson when it comes to running the football, but the Jaguars quarterback is still a threat to scramble or take off with the ball. Lawrence has 23 career rushing touchdowns, including a career-high nine in 2025. While he doesn’t have one through the first four weeks of this season, that could change Sunday against the Eagles.

Philadelphia allowed Washington quarterback Jayden Daniels to average 6.2 yards per carry on five attempts in Week 1 before surrendering two rushing touchdowns to Tennessee quarterback Cam Ward in Week 2 and another to veteran quarterback Case Keenum in Week 3 against Chicago.

Jaguars running backs Bhayshul Tuten and Chris Rodriguez Jr. have each scored two rushing touchdowns this season, and the Stats Hub notes that Rodriguez’s two scores have come in Jacksonville’s last two games. The Stats Hub also notes that the Jaguars have scored the first touchdown in each of their last five games.

While none of those touchdown trends directly involve Lawrence finding the end zone, they help illustrate Jacksonville’s ability to score on the ground and create opportunities near the goal line. Given Lawrence’s rushing touchdown production last season and Philadelphia’s struggles against mobile quarterbacks this year, he could be another threat to find the end zone Sunday.

  • Trevor Lawrence Anytime Touchdown (+300)

Jalen Hurts Over 27.5 Rushing Yards (-115)

Jalen Hurts doesn’t quite have the supporting cast around him that he expected coming into this season due to a slew of injuries, so he’s going to have to create some plays on his own to give the Eagles a chance to win Sunday’s game against the Jaguars.

Hurts is one of those quarterbacks who can be dynamic with his legs. He proved that during the first few years of his career, but he has dialed it back somewhat over the last two seasons.

The Eagles will feature a new-look offensive line this week and are dealing with key injuries at their skill positions, so Hurts may need to channel his former self and make plays with his legs. He has already made a few big plays on the ground this season, but he has only 21 rushing attempts through the first four weeks. That may need to change against the Jaguars.

The Stats Hub notes that Hurts has recorded 25 or more rushing yards in 20 of his last 23 appearances with the Eagles as underdogs. He has also rushed for 25 or more yards in two of Philadelphia’s first four games this year, including 46 against Washington in Week 1.

The Jaguars have allowed only one quarterback to rush for more than 27.5 yards this season, and that was back in Week 1 against Cleveland when Deshaun Watson recorded 38 rushing yards. However, none of the quarterbacks Jacksonville has faced this season are quite as dangerous as Hurts can be as a runner.

  • Jalen Hurts Over 27.5 Rushing Yards (-115)

Most-Bet Eagles vs. Jaguars Player Props

If those two props weren’t enough, check out the top five most-bet Overs and top five most-bet Unders for player props below:

Top 5 Most-Bet Player Prop Overs

  1. Bhayshul Tuten – Over 0.5 Anytime Touchdowns 
  2. Parker Washington – Over 0.5 Anytime Touchdowns
  3. Jalen Hurts – Over 0.5 Anytime Touchdowns
  4. Trevor Lawrence – To Record 200+ Pass Yards (Over 199.5)
  5. Trevor Lawrence – To Record 175+ Pass Yards (Over 174.5)

Top 5 Most-Bet Player Prop Unders

  1. Jalen Hurts – Under 27.5 Rushing Yards
  2. Jalen Hurts – Under 185.5 Passing Yards
  3. Trevor Lawrence – Under 226.5 Passing Yards
  4. Trevor Lawrence – Under 19.5 Pass Completions
  5. Trevor Lawrence – Under 14.5 Rushing Yards

Eagles vs. Jaguars Game Info

  • 📍 Where: Tottenham Hotspur Stadium, London, England
  • đź“… Date: Sunday, Oct. 11
  • ⏰ Kickoff: 9:30 AM ET
  • 📺💻 TV/Streaming: NFL Network

Referenced odds are subject to change.

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Michael Hennelly

Michael has been an active sports contributor for multiple publications since graduating from Penn State in 2024. While sports play a major role in his life (in the best way), he also enjoys spending time with family and friends. Contact Michael at michael.hennelly at hardrockdigital.com.