Champions League soccer is back as the Round of 16 begins this afternoon with four compelling first-leg matchups across Europe. Away goals are no longer a tiebreaker, so the emphasis shifts to execution, game management, and positioning ahead of the return legs next week.
Here are the current Champions League last 16 first leg odds from Hard Rock Bet Sportsbook:
Liverpool at Galatasaray
- When & Where: 1:45 p.m. ET | Rams Park (Istanbul)
- TV: Paramount+ (US)
- 1st Leg Favorite: Liverpool -140
- Odds to Advance:
- Liverpool -700 to Qualify for the Round of 8
- Galatasaray +450 to Qualify for the Round of 8
Liverpool open their knockout campaign in one of Europe’s most hostile environments. Galatasaray’s home record in continental competition has long been formidable, and the atmosphere in Istanbul often plays as an extra defender.
For Liverpool, the challenge will be balancing aggression with discipline. Arne Slot’s side plays well in transition, but away first legs require patience. An early goal would dramatically shift the tone, but avoiding defensive lapses against a crowd-fueled Galatasaray attack is just as critical.
Take a road goal – even a narrow win or draw would be a strong result heading back to Anfield. Liverpool are -140 favorites in Turkey today, and bettors can back Galatasaray at +350 to win on their home field. The tie is available at +300.
Popular props for Liverpool vs Galatasaray
- Hugo Ekitke Anytime Goalscorer
- Victor Osimhen Anytime Goalscorer
- Dominik Szoboszlai over 1.5 shots
Tottenham at Atletico Madrid
- When & Where: 4:00 p.m. ET | Riyadh Air Metropolitano (Madrid)
- TV: Paramount+ (US)
- 1st Leg Favorite: Atletico Madrid -140
- Odds to Advance:
- Atletico Madrid -250 to Qualify for the Round of 8
- Tottenham +175 to Qualify for the Round of 8
Atletico Madrid remain one of the most tactically disciplined knockout teams in Europe. Diego Simeone’s side thrives in tight, physical matches where margins are razor-thin. They concede space rarely and punish mistakes ruthlessly. They’re the betting favorite in this first leg at -140 on the moneyline.
Tottenham, by contrast, can take a break from their Premier League relegation battle with an opportunity to do something special – advance to the Champions League quarterfinals. Spurs’ attacking pieces can stretch defenses vertically, but breaking down Atletico’s low block is a different challenge altogether. The London side are the underdog today in Madrid, you can bet them to win at +400. The tie is also available at +275.
Whoever advances to the Round of 8 here will be thinking they have a realistic shot at making the Champions League Final, after the kind draw.
Popular props for Tottenham vs Atletico Madrid
- Julian Alvarez Anytime Goalscrorer
- Alexander Sørloth Anytime Goalscorer
- Julian Alvarez over 2.5 shots
Barcelona at Newcastle
- When & Where: 4:00 p.m. ET | St. James’ Park
- TV: Paramount+ (US)
- 1st Leg Favorite: Barcelona +140
- Odds to Advance:
- Barcelona: -300 to Qualify for the Round of 8
- Newcastle United: +225 to Qualify for the Round of 8
Barcelona return to the UCL knockout stage with a difficult away assignment against a Newcastle United side energized by its European resurgence. St. James’ Park under the lights presents a unique intensity. Newcastle’s physicality and pressing can disrupt rhythm-based teams – and Barcelona traditionally prefer control and structured buildup.
With that said, Barcelona enter the first leg of the tie as a +140 favorite, while Newcastle is currently +165 to defend their home field with a win – this might be a tight one. You can bet the draw at +300.
Popular props for Barcelona vs Newcastle United
- Lamine Yamal over 1.5 shots on target
- Lamine Yamal anytime goalscrorer
- Anthony Gordon over 0.5 shots on target
Bayern Munich at Atalanta
- When & Where: 4:00 p.m. ET | Gewiss Stadium (Bergamo)
- TV: Paramount+ (US)
- 1st Leg Favorite: Bayern Munich -160
- Odds to Advance:
- Bayern Munich: -850 to Qualify for the Round of 8
- Atalanta: +500 to Qualify for the Round of 8
Atalanta are fearless and aggressive, known for their attacking system and willingness to commit numbers forward. They won’t sit back – especially at home. They’re available as a home underdog at +375.
Bayern Munich, however, are built for this stage. Their experience, depth, and clinical finishing often show in knockout scenarios. They’re currently second-favorites to win the whole tournament, and are heavily favored to both advance to the round of 8 (-850), and win in Italy today (-160). The draw is priced at +350.
Popular props for Bayern Munich vs Atalanta
- Harry Kane anytime goalscorer
- Luis Díaz anytime goalscorer
- Lennart Karl 2+ shots on goal
All referenced odds are subject to change.
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